Kentucky will head to No. 11 Louisville on Tuesday night for a true road game against the Cardinals.
If the opening lines hold, the Wildcats will be underdogs in the early-season rivalry game.
Louisville opened as 3.5-point favorite at Fan Duel.
FanDuel has issued the first line for Tuesday’s matchup of Louisville vs Kentucky basketball.
Cards favored by -3.5 pic.twitter.com/FxS4MpKGWJ
— Mark Blankenbaker (@UofLSheriff50) November 9, 2025
Tip time is scheduled for 8 p.m. ET Tuesday and the game will air live on ESPN.
